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This information is intended for UK healthcare professionals only.

This video has been commissioned and developed by Pfizer Ltd.

  • Osteoarthritis (OA) is the single most common cause of disability in older adults.1
  • People with OA often experience depression, impaired physical functioning, and ability to perform daily activities.
  • One in five people consult primary and secondary care about a musculoskeletal problem in England.3
  • OA may be associated with some types of cardiovascular disease.4
  • Chronic pain caused by OA has an impact on:2,5–9
    • family
    • daily life
    • mental health
    • healthy ageing
    • heart health
    • work
    • ability to keep active.


  1. Kaplan W et al. WHO: Priority medicines for Europe and the World 2013 Update. 2013: Chapter 6 Section 12. Available at: (accessed May 2021)
  2. OARSI. Osteoarthritis: A Serious Disease, Submitted to the U.S. Food and Drug Administration. December 1, 2016
  3. Jordan KP, Jöud A, Bergknut C, et al International comparisons of the consultation prevalence of musculoskeletal conditions using population-based healthcare data from England and Sweden. Annals of the Rheumatic Diseases 2014;73:212-218.
  4. Hall AJ, et al. Eur J Prev Cardiol 2016; 23: 937–46
  5. Martire LM, et al. Pain 2013; 154: 1725–31
  6. Wilkie R, et al. Rheumatology 2014; 53: 459–64
  7. Agarwal P and Sambamoorthi U. J Gen Int Med 2015; 30: 1803–11
  8. Clynes MA, et al. Aging Clin Exp Res 2019; 31: 1049–56
  9. Conaghan PG, et al. Rheumatology 2015; 54: 270–77




Date of preparation: May 2021