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This information is intended for UK healthcare professionals only.

This video has been commissioned and developed by Pfizer.

Many physiological processes drive the development of chronic musculoskeletal pain experienced in conditions such as:

  • osteoarthritis
  • rheumatoid arthritis
  • tendinitis
  • chronic back pain

One of these processes is peripheral sensitisation, a state in which receptors or peripheral sensory neurons at the site of pain become abnormally responsive to stimuli.1

This video details the causes of peripheral sensitisation and its role in the development of chronic pain. 



  1. McGreevy K, Bottros MM, Raja SN. Preventing chronic pain following acute pain: risk factors, preventative strategies, and their efficiency. Eur J Pain Suppl. 2011;5:365-372.




Date of preparation: May 2021