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This information is intended for UK healthcare professionals only.

This video has been commissioned and developed by Pfizer.


Throughout the world, 1 in 5 people suffer from moderate to severe chronic pain.1–4

Chronic pain can have a significant negative impact on those afflicted, with effects including sleeplessness, decreased activity, and mood changes such as depression.5

This video details the different pathophysiologies of acute and chronic pain.



  1. Breivik H, Collet B, Ventafridda V, Cohen R, Gallacher D. Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment. Eur J Pain. 2006;10:287-333. 
  2. Schopflocher D, Taenzer P, Jovey R The prevalence of chronic pain in Canada. Pain Res Manag. 2011;16:445-450. 
  3. Johannes CB, Le TK, Zhou X, Johnston JA, Dworkin RH. The prevalence of chronic pain in United States adults: results of an Internet-based survey. J Pain. 2010;11:1230-1239. 
  4. Bouhassira D, Lantéri-Minet M, Attal N, Laurent B, Touboul C. Prevalence of chronic pain with neuropathic characteristics in the general population. Pain. 2008;136:380-387.  
  5. OARSI. Osteoarthritis: A Serious Disease, Submitted to the U.S. Food and Drug Administration. December 1, 2016




Date of preparation: May 2021